Participate in Research at Holland Bloorview

Holland Bloorview’s research institute conducts need-based and ground breaking health research to make a real-world impact in the lives of children and youth with a disability, and their families.

Select from the categories below to find a research study that is right for you – there are many opportunities to get involved.

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Find a research study

To find studies most relevant to you and/or your child, use the filters below to choose diagnoses and/or research areas that meet your interests.

Diagnosis or medical condition
Research Area

List of research studies

The Effect of Multi-Session Transcranial Direct Current Stimulation (tDCS) on Cognitive Performance in Youth with Persisting Concussion Symptoms


Some youth with concussion have symptoms weeks after their injury, like problems doing more than one thing at a time. We want to see if transcranial direct current stimulation (tDCS), which delivers a low level of electricity to the brain, can help reduce these symptoms.

Participate in this study:

Do you have trouble with lasting symptoms after a concussion? Participate in a clinical trial about non-invasive brain stimulation.

A randomized placebo-controlled trial of tideglusib vs. placebo in the treatment of adolescents with ASD


Currently conducting clinical trials to investigate whether a drug called tideglusib helps to improve symptoms of Autism Spectrum Disorder, specifically social engagement, social function, and repetitive behaviours. 

Participate in this study:

Have you been diagnosed with an autism spectrum disorder?  Do you have social difficulties and/or repetitive behaviours?  You may be eligible to participate in a clinical trial of a medication called tideglusib.


Neuro-Exergaming for All: Bringing Fun, Social Engagement, and Physical Activity to Children with Cerebral Palsy


Exercise video games (“exergames”) are a novel approach to engage youth with cerebral palsy (CP) in physical exercise and social interaction with their peers. To date, our team has developed an accessible and functional recumbent bicycling-based exergaming system, called the Liberi exergame. In this project, we are extending the capabilities of our exergames system to allow people of different physical abilities to play together by using different balancing algorithms built into the games to automatically adjust the difficulty of the game to match the player’s abilities. This study will evaluate how well these balancing mechanisms work and how to improve them for fun and fair game-play.

Participate in this study:

Are you a youth with cerebral palsy (CP) interested in playing fun and exciting video games with other kids while engaging in physical activity? If so, consider joining this study!

Investigating Mental Activation with and without Performance of Mental Tasks


We are currently recruiting typically developing individuals between the ages of 13 and 18 years for a research study on brain-computer interfaces. This research will contribute to the development of a communication device for individuals with severe motor impairment. This study will use near infrared spectroscopy (NIRS), which allows detection of brain activity by measuring changes in brain oxygen levels during performance of mental tasks.

Participate in this study:

Do you want to participate in a study that may help develop a communication device for individuals with severe motor impairment? Consider participating in our study.

Investigating the Efficacy of Meditation and Mental Rehearsal on EEG BCI Performance in a Paediatric Context


We are looking to measure changes in brain activity during a mental task, and whether mindfulness meditation has any effect on that. This study aims to enhance the real-world applicability of a technology that can allow persons with severe motor impairments to communicate and interact with their environment. Brain electrical activity will be measured using a non-invasive technique called electroencephalography (EEG). 

Participate in this study:

Are you a typically developing person between 10 and 18 years old? If you’d like to help the advancement of a technology that may benefit persons with severe motor disorders, consider participating in our study!