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Autism Research Centre - Publications

Little boy with computer tablet in a library.

The Autism Research Centre seeks to improve the function and quality of life of children with autism spectrum disorders (ASD or autism) and their families through research.

Here is a selection of the published Autism research results:

Dr. Evdokia Anagnostou

  • Lord, C., Charman, T., Havdahl, A., Carbone, P., Anagnostou, E., Boyd, B., Carr, T., de Vries, P. J., Dissanayake, C., Divan, G., Freitag, C. M., Gotelli, M. M., Kasari, C., Knapp, M., Mundy, P., Plank, A., Scahill, L., Servili, C., Shattuck, P., Simonoff, E., … McCauley, J. B. (2021). The Lancet Commission on the future of care and clinical research in autism. Lancet (London, England), S0140-6736(21)01541-5. Advance online publication. https://doi.org/10.1016/S0140-6736(21)01541-5.
  • Loureiro, L. O., Howe, J. L., Reuter, M. S., Iaboni, A., Calli, K., Roshandel, D., Pritišanac, I., Moses, A., Forman-Kay, J. D., Trost, B., Zarrei, M., Rennie, O., Lau, L., Marshall, C. R., Srivastava, S., Godlewski, B., Buttermore, E. D., Sahin, M., Hartley, D., Frazier, T., … , Anagnostou, E., Scherer, S. W. (2021). A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder. NPJ genomic medicine, 6(1), 91. https://doi.org/10.1038/s41525-021-00254-0.
  • Gharehgazlou, A., Vandewouw, M., Ziolkowski, J., Wong, J., Crosbie, J., Schachar, R., Nicolson, R., Georgiades, S., Kelley, E., Ayub, M., Hammill, C., Ameis, S. H., Taylor, M. J., Lerch, J. P., & Anagnostou, E. (2021). Cortical Gyrification Morphology in ASD and ADHD: Implication for Further Similarities or Disorder-Specific Features?. Cerebral cortex (New York, N.Y. : 1991), bhab326. Advance online publication. https://doi.org/10.1093/cercor/bhab326.
  • Soorya, L. V., Fogg, L., Ocampo, E., Printen, M., Youngkin, S., Halpern, D., Kolevzon, A., Lee, S., Grodberg, D., & Anagnostou, E. (2021). Neurocognitive Outcomes from Memantine: A Pilot, Double-Blind, Placebo-Controlled Trial in Children with Autism Spectrum Disorder. Journal of child and adolescent psychopharmacology, 31(7), 475–484. https://doi.org/10.1089/cap.2021.0010.
  • Kushki, A., Cardy, R. E., Panahandeh, S., Malihi, M., Hammill, C., Brian, J., Iaboni, A., Taylor, M. J., Schachar, R., Crosbie, J., Arnold, P., Kelley, E., Ayub, M., Nicolson, R., Georgiades, S., Lerch, J. P., & Anagnostou, E. (2021). Cross-Diagnosis Structural Correlates of Autistic-Like Social Communication Differences. Cerebral cortex (New York, N.Y. : 1991), 31(11), 5067–5076. https://doi.org/10.1093/cercor/bhab142.
  • Cost, K. T., Crosbie, J., Anagnostou, E., Birken, C. S., Charach, A., Monga, S., Kelley, E., Nicolson, R., Maguire, J. L., Burton, C. L., Schachar, R. J., Arnold, P. D., & Korczak, D. J. (2021). Mostly worse, occasionally better: impact of COVID-19 pandemic on the mental health of Canadian children and adolescents. European child & adolescent psychiatry, 1–14. Advance online publication. https://doi.org/10.1007/s00787-021-01744-3.

Dr. Jessica Brian

  • Brian, J., Drmic, I., Roncadin, C., Dowds, E., Shaver, C., Smith, I.M., Zwaigenbaum, L., Sacrey, L., Bryson, S.E. (2022). Effectiveness of a parent-mediated intervention for toddlers with autism spectrum disorder: Evidence from a large community implementation. Autism. January 2022. doi:10.1177/13623613211068934.
  • Grzadzinski, R., Amso, D., Landa, R., Watson, L., Guralnick, M., Zwaigenbaum, L., Deák, G., Estes, A., Brian, J., Bath, K., Elison, J., Abbeduto, L., Wolff, J., & Piven, J. (2021). Pre-symptomatic intervention for autism spectrum disorder (ASD): defining a research agenda. Journal of neurodevelopmental disorders, 13(1), 49. https://doi.org/10.1186/s11689-021-09393-y.
  • Sacrey, L. R., Zwaigenbaum, L., Brian, J. A., Smith, I. M., Armstrong, V., Raza, S., Vaillancourt, T., & Schmidt, L. A. (2021). Affect and gaze responses during an Emotion-Evoking Task in infants at an increased likelihood for autism spectrum disorder. Molecular autism, 12(1), 63. https://doi.org/10.1186/s13229-021-00468-0.
  • Patterson, J. W., Armstrong, V., Duku, E., Richard, A., Franchini, M., Brian, J., Zwaigenbaum, L., Bryson, S. E., Sacrey, L. R., Roncadin, C., & Smith, I. M. (2021). Early trajectories of motor skills in infant siblings of children with autism spectrum disorder. Autism research : official journal of the International Society for Autism Research, 10.1002/aur.2641. Advance online publication. https://doi.org/10.1002/aur.2641.
  • Cardy, R. E., Dupuis, A., Anagnostou, E., Ziolkowski, J., Biddiss, E. A., Monga, S., Brian, J., Penner, M., & Kushki, A. (2021). Characterizing Changes in Screen Time During the COVID-19 Pandemic School Closures in Canada and Its Perceived Impact on Children With Autism Spectrum Disorder. Frontiers in psychiatry, 12, 702774. https://doi.org/10.3389/fpsyt.2021.702774.
  • Teskey, G., Anagnostou, E., Mankad, D., Smile, S., Roberts, W., Brian, J., Bowdish, D., & Foster, J. A. (2021). Intestinal permeability correlates with behavioural severity in very young children with ASD: A preliminary study. Journal of neuroimmunology, 357, 577607. https://doi.org/10.1016/j.jneuroim.2021.577607

Dr. Azadeh Kushki

  • Nguyen, J., Cardy, R. E., Anagnostou, E., Brian, J., & Kushki, A. (2021). Examining the effect of a wearable, anxiety detection technology on improving the awareness of anxiety signs in autism spectrum disorder: a pilot randomized controlled trial. Molecular autism, 12(1), 72. https://doi.org/10.1186/s13229-021-00477-z.
  • Kushki, A., Cardy, R. E., Panahandeh, S., Malihi, M., Hammill, C., Brian, J., Iaboni, A., Taylor, M. J., Schachar, R., Crosbie, J., Arnold, P., Kelley, E., Ayub, M., Nicolson, R., Georgiades, S., Lerch, J. P., & Anagnostou, E. (2021). Cross-Diagnosis Structural Correlates of Autistic-Like Social Communication Differences. Cerebral cortex (New York, N.Y. : 1991), 31(11), 5067–5076. https://doi.org/10.1093/cercor/bhab142.
  • Malihi, M., Nguyen, J., Cardy, R. E., Eldon, S., Petta, C., & Kushki, A. (2020). Short report: Evaluating the safety and usability of head-mounted virtual reality compared to monitor-displayed video for children with autism spectrum disorder. Autism : the international journal of research and practice, 24(7), 1924–1929. https://doi.org/10.1177/1362361320934214.
  • Malihi, M., Nguyen, J., Cardy, R. E., Eldon, S., Petta, C., & Kushki, A. (2020). Data-Driven Discovery of Predictors of Virtual Reality Safety and Sense of Presence for Children With Autism Spectrum Disorder: A Pilot Study. Frontiers in psychiatry, 11, 669. https://doi.org/10.3389/fpsyt.2020.00669.

Dr. Melanie Penner

  • Agnihotri, S., Penner, M., Mallory, K. D., Xie, L., Hickling, A., Joachimides, N., Widgett, E., & Scratch, S. E. (2021). Healthcare utilization and costs associated with persistent post-concussive symptoms. Brain injury, 35(11), 1382–1389. https://doi.org/10.1080/02699052.2021.1972151.
  • Duncan, A., Luong, D., Perrier, L., Bayley, M. T., Andrew, G., Arbour-Nicitopoulos, K., Chan, B., Curran, C. J., Dimitropoulos, G., Hartman, L., Huang, L., Kastner, M., Kingsnorth, S., McCormick, A., Nelson, M., Nicholas, D., Penner, M., Thompson, L., Toulany, A., Woo, A., … Munce, S. (2021). Prioritizing a Research Agenda of Transitional Care Interventions for Childhood-Onset Disabilities. Frontiers in pediatrics, 9, 682078. https://doi.org/10.3389/fped.2021.682078.
  • Das, J., Hartman, L., King, G., Jones-Stokreef, N., Moore Hepburn, C., & Penner, M. (2021). Perspectives of Canadian Rural Consultant Pediatricians on Diagnosing Autism Spectrum Disorder: A Qualitative Study. Journal of developmental and behavioral pediatrics : JDBP, 10.1097/DBP.0000000000001006. Advance online publication. https://doi.org/10.1097/DBP.0000000000001006.
  • McDonnell, C. G., DeLucia, E. A., Hayden, E. P., Penner, M., Curcin, K., Anagnostou, E., Nicolson, R., Kelley, E., Georgiades, S., Liu, X., & Stevenson, R. A. (2021). Sex Differences in Age of Diagnosis and First Concern among Children with Autism Spectrum Disorder. Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53, 50(5), 645–655. https://doi.org/10.1080/15374416.2020.1823850.
  • Makino, A., Hartman, L., King, G., Wong, P.Y., & Penner, M. (2021). Parent Experiences of Autism Spectrum Disorder Diagnosis: a Scoping Review. Rev J Autism Dev Disord 8, 267–284. https://doi.org/10.1007/s40489-021-00237-y