Neurophysiological Biomarkers and Effects of Robotic Assisted Mobility Training in Children with Motor Impairments

Summary

We are studying how the brain and muscles activate and coordinate movement in children with motor impairments, such as cerebral palsy, using a robotic exoskeleton. The study aims to understand how robotic-assisted therapy supports movement control and brain function in these children, ultimately improving their confidence and ability to participate in daily life activities.

Researcher(s)

Dr. Tom Chau, Dr. Virginia Wright, Yara Corky (PhD candidate)

Call to action

Is your child between the ages of 4-12 years and typically developing, or between the ages of 4-12 years and has cerebral palsy? Consider joining a study that explores the effects of a child-friendly exoskeleton robotic-assisted walking on the brain and muscle activity.

Who can participate

  • Children aged 4–12 years
  • Typically developing (no diagnosed neurological or motor disorders)
  • Able to walk independently without mobility aids
  • Have a height that falls roughly between 85 cm and 130 cm (about 2’9” to 4’3”) and weigh up to 56 kg (125 lbs) 
  • Able to reliably express discomfort or fatigue and can participate in a full gym program at school.
  • No seizure disorders, open skin lesions, or medical restrictions to physical activity

OR

  • Children aged 4–12 years
  • Have cerebral palsy or similar neuromotor condition 
  • Use a walker (GMFCS III or IV) and able to walk for at least one minute at a time with their walker 
  • Have a height that falls roughly between 85 cm and 130 cm (about 2’9” to 4’3”) and weigh up to 56 kg (125 lbs) 
  • Able to reliably express discomfort or fatigue 
  • No seizure disorders, open skin lesions, or medical restrictions to physical activity
  • No medical procedures or Botox injections in the lower limbs done in the last 6 months

Funding agency

Tri-Council (NSERC), and Weston Family foundation

What's involved

Your child will participate in one or two testing sessions lasting 2 hours at Holland Bloorview Kids Rehabilitation Hospital. Your child will wear a robotic lower-limb exoskeleton (called Trexo) for overground walking while we record:

  • Brain activity using a non-invasive cap with sensors.
  • Muscle activity using wireless sensors on the legs and lower back.
  • Body movement using video recordings.

A pediatric physiotherapist will support your child during walking trials. Breaks will be offered, and you may stay in the room for reassurance.

Deadline

Interested in participating

If you are interested in participating in this study or have questions, please contact Yara Corky at 416-425-6220 ext. 3169 or ycorky@hollandbloorview.ca.

Additional information

31/10/2025 eREB #759

Brain and Muscle Responses to Robotic Training in Children with Motor Impairments

Learn more about this study