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Participate in Research at Holland Bloorview

The Bloorview Research Institute is conducting need-based and ground breaking health research. There are many opportunities for research participation in our ongoing studies.

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Finding the Right Research Study

To find the studies that are relevant to you, use the filters to choose any diagnoses and/or research areas that reflect your interest.  

To view current studies that are not actively recruiting, uncheck the “Actively Recruiting” filter and all Bloorview Research Institute research studies will be displayed.

Diagnosis or medical condition
Research Area
 

List of research studies

Systematic Quantification of Systemic Blood Flow in Near Infrared Spectroscopy Brain Computer Interfaces in a Pediatric Context

Summary:

We invite you to take part in a research study to help develop a communication device for children with severe motor impairment.


Participate in this study:

We invite you to take part in a research study to help develop a communication device for children with severe motor impairment.

A randomized placebo-controlled trial of tideglusib vs. placebo in the treatment of adolescents with ASD

Summary:

Currently conducting clinical trials to investigate whether a drug called tideglusib helps to improve symptoms of Autism Spectrum Disorder, specifically social engagement, social function, and repetitive behaviours. 

Participate in this study:

Have you been diagnosed with an autism spectrum disorder?  Do you have social difficulties and/or repetitive behaviours?  You may be eligible to participate in a clinical trial of a medication called tideglusib.

 

Autonomic nervous system response to stress in children after mild traumatic brain injury (mTBI) compared to non-injured controls: a pilot study

Summary:

We want to study how the body changes in response to stress in children recovering from a concussion. Stress can sometimes cause changes in heart rate, breathing, and skin temperature.  Some children after a concussion have symptoms such as headache that are triggered or worsened by stress.  In the future it may help us better tailor treatments to help these children manage stressful situations.

Participate in this study:

Does your child or teenager experience post-concussion symptoms? Consider participating in our study!

Childhood Cerebral Palsy Integrated Neuroscience Discovery Network “CP-NET” – Clinical Database Platforms

Summary:

The Childhood Cerebral Palsy (CP) Integrated Neuroscience Discovery Network “CP-NET” is designed to bring together children with CP, their families, and clinical and basic scientists to foster neuroscience discoveries through integrated translation. Understanding the underlying neuroscience mechanisms, pathology, physiology, and genomics of CP is critical to developing improved treatments.  In particular there is a critical need to link translationally-oriented neuroscience research with cutting-edge neurorehabilitation approaches for CP. 

 

In this study, the CP-NET Clinical Database Platforms, we will create a population-based database of CP that integrates detailed information about risk factors, neuropathology, neurodevelopmental and psychosocial status and genomics.  In this study, we will recruit a population-based cohort of children with CP born after Jan 1, 2009 from 8 children’s treatment centres across Ontario. Data will be gathered initially at baseline, confirmed at 5 years of age, and additional data will be collected again when the child is 7 years of age (if before June 30, 2018).


The core element of CP-NET is the Clinical Database Platform consisting of five clinical database platforms. The Clinical Risk Factor Platform will detail risk variables from neonatal and maternal health records.  Neuroimaging exams that have previously been done for clinical purposes will be obtained, read, coded, and analyzed to create the Neuroimaging Platform.  Saliva samples will be obtained and DNA stored for the creation of the Genomic Platform.  Standardized developmental outcome measures including a neurological exam, identification of co morbidities, cognitive profile, pain assessment, and gross motor, fine motor, and communication classifications will be administered to create the Neurodevelopmental Platform.  Finally, assessment of mental health, sleep, quality of life and participation will comprise the Psychosocial & Participation Platform.

Participate in this study:

Has your child been diagnosed with Cerebral Palsy (CP)? Consider participating in one or both of our research studies:

CP-NET

and/or

The Canadian Cerebral Palsy Registry

We’re working on building two databases of information about kids in Ontario (CP-NET) and across Canada (The Canadian CP Registry) who have been diagnosed with CP.  Our goal is to better understand how many kids are affected by CP in different parts of Ontario and Canada and to better understand the causes of CP.  We’re hoping that learning more about what causes CP will transform care and treatments for children and their families.”

Evaluating current questionnaires of client and caregiver involvement in outpatient appointments

Summary:

Our research team thinks that you can help us understand the ways in which children/youth and parents/caregivers feel involved and not involved in their appointments.

Participate in this study:

Are you a Holland Bloorview client who does Lokomat training? Want to help us evaluate current questionnaires of client involvement in outpatient appointments? Consider participating in our study so that we can make our questionnaires the best they can be!


Bloorview Research Institute

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Frequently asked questions (FAQ)

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