The workhorse in our research is multimodal
Magnetic Resonance Imaging of brain structure and function (MRI). Insights about genetic underpinnings of various MR-derived phenotypes are
gained through large Genome-wide Association Studies (GWAS). Dynamics of gene expression, as it relates to MRI-derived phenotypes, such as
cortical thickness, is revealed by integrating data from the Allen Human Brain Atlas and the BrainSpan Atlas. Epigenetic signatures are explored via
Epigenome-wide Association Studies.
Influences of social and physical environment are studied through geo-spatial
links between aggregate data (e.g., green space or income inequality in a
neighbourhood) and health data obtained from our participants.