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Research Ethics Board (REB)

The Holland Bloorview Research Ethics Board (REB) is an independent committee established by the Holland Bloorview Kids Rehabilitation Hospital. The REB provides independent, multidisciplinary ethics review of research involving humans that is conducted at Holland Bloorview or by staff of Holland Bloorview, Bloorview Research Institute, and the Bloorview School Authority. It has the authority to approve, reject, request modifications to, or terminate any proposed or ongoing research.

The REB is independent in their decision-making, and they are required to operate free of inappropriate influence, including situations of real, potential or perceived conflict of interest.

The REB is responsive to changing ‘best practices’ in research ethics and will attend to developments at the local, national, and international levels. The REB will adhere the ICH Guidance E6: Good Clinical Practice Consolidated Guideline; Health Canada Division 5 of the Food and Drug Regulations; the Ontario Personal Health Information Protection Act 2004; the U.S. Office for Human Research Protection (OHRP) directives; and the requirements of the Department of Health and Human Services (HHS) Protection of Human Subjects regulations, 45 CFR part 46, and other relevant international declarations, such as the Helsinki Declaration on Research Ethics.

The Holland Bloorview Research Ethics Board (REB) ensures that all research involving human participants carried out at Holland Bloorview Kids Rehabilitation Hospital (Holland Bloorview) or by Holland Bloorview staff, is conducted in accordance with the highest scientific and ethical standards.

Click here to view the Research Ethics Board Terms of Reference .

REB Board Members

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